English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

This study aimed to design a new method for rapid and accurate detection of carbapenemase phenotypes based on the simplified carbapenem inactivation method (sCIM). We evaluated the sensitivity and specificity of the method, called the rapid carbapenemase detection method (rCDM), for the detection of carbapenemase-producing  Enterobacteriaceae  and  Pseudomonas aeruginosa . A total of 257  Enterobacteriaceae , 236  P. aeruginosa , and 20  Acinetobacter baumannii  isolates were tested. Phenotypic evaluations were performed using rCDM, sCIM, and mCIM. For  Enterobacteriaceae , the sensitivity of rCDM was 100% and the specificity was 99.6%. For  P .  aeruginosa , the sensitivity of rCDM was 97.4% and the specificity was 100%. Carbapenemase-producing  A. baumannii  were not detected by rCDM. The concordance rate of rCDM and sCIM for  Enterobacteriaceae  and  P. aeruginosa  was 99.8%, with the exception of one  P. aeruginosa  isolate that expressed the  bla   VIM −4  gene. The concordance rate of rCDM and mCIM for  Enterobacteriaceae  and  P. aeruginosa  was 100%. rCDM can be used to accurately detect carbapenemase-producing  Enterobacteriaceae  and  P. aeruginosa  in 5–6 h and is suitable for routine use in most clinical microbiology laboratories.

frontiers in cellular and infection microbiology

The Rapid Carbapenemase Detection Method (rCDM) for Rapid and Accurate Detection of Carbapenemase-Producing Enterobacteriaceae and Pseudomonas aeruginosa