English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The environmental control of invasin ( inv ) expression in  Yersinia enterocolitica  is mediated by a regulatory network composed of negative and positive regulators of  inv  gene transcription. Previously, we demonstrated that OmpR, a response regulator of the two-component signal transduction pathway EnvZ/OmpR, negatively regulates  inv  gene expression in  Y. enterocolitica  O9 by direct interaction with the  inv  promoter region. This study was undertaken to clarify the role of OmpR in the  inv  regulatory circuit in which RovA protein has been shown to positively regulate  inv  transcription. Using  ompR ,  rovA , and  ompR rovA Y. enterocolitica  mutant backgrounds we showed that the inhibitory effect of OmpR on  inv  transcription may be observed only when RovA is present/active in  Y. enterocolitica  cells. To extend our research on  inv  regulation we examined the effect of OmpR on  rovA  gene expression. Analysis of  rovA-lacZ  transcriptional fusion in  Y. enterocolitica  wild-type and  ompR  background indicated that OmpR does not influence  rovA  expression. Thus, our results indicate that OmpR influences  inv  expression directly via binding to the  inv  promoter, but not through modulation of  rovA  expression.

OmpR, a response regulator of the two-component signal transduction pathway, influences inv gene expression in Yersinia enterocolitica O9