English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Herpes-associated erythema multiforme is the most frequent form and occurs in 50-93% of patients with exudative erythema multiforme (EEM) [6, 8]. Erythema multiforme relapses in at least 30% of patients. A considerable number of causes for the infectious-allergic form of erythema have been detected, and clinical manifestations of infectious herpes are found in about half of patients [7]. The trigger role of herpes simplex virus in the pathogenesis of EEM gives objective reasons to proscribe acyclic nucleosides to such patients [1, 2]. In the literature of the field, one can find statements that the monotherapy of EEM by acyclic nucleosides is not effective enough [4, 5]. In many cases, psycho-emotional stress has a role in precipitating or triggering a herpes simplex relapse which comes prior to HAEM development. Because of what has been said, it appears important to study the connection between the immune system and the nervous system, and to search for new combined methods for adequate therapy to treat herpesassociated erythema multiforme, while taking into account the peculiarities of innate and adaptive functioning of the immune system. This article uses the MNRI® (Masgutova Neurosensorimotor Reflex Integration®) therapeutic program developed by Dr. S. Masgutova, which includes diagnostic and therapeutic procedures [3]. The purpose of this study is to investigate the effect of the MNRI® therapeutic program on the innate and adaptive immune systems functions, and the peculiarity of cells cooperation in the immune response at the patients with HAEM. Materials and Methods In this research, two groups of patients were involved: Control Group-A – 15 healthy individuals (8 males and 7 females, age range of 18-54), and Research Group (B and C) – 31 patients (age range of 25-40 years old) with HAEM. The duration of the HAEM disease varied from two to ten years with a frequency of relapse of one to two times per year. The laboratory DNA diagnostics identified the herpesviridae virus in these 27 patients. The research group consisted of two other sub-groups: B) combined MNRI® and standard treatment – 16 patients (7 males and 9 females) and C) only standard treatment – 15 patients (8 males and 7 females). Results of treatments of patients with HAEM in Group-B MNRI® therapy sessions for 14 days (6-8 hours daily) and standard treatment were compared with results of Group-C (standard treatment only: chemotherapeutic agents – acyclic nucleosides (acyclovir, Zovirax, viroleks, valacyclovir, and famciclovir). The Control Group-A of clinically healthy individuals served as About Submit Journals 6 My frontiers

Influence of Neuro-Sensory-Motor Reflex Integration Technique on Immune Response of Patients with Herpes-Associated Multiforme Erythema