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Benzothiazole is the heterocyclic compound formed from 2-aminothiophenol substituted aromatic aldehyde by using zinc oxide nanoparticles and because of their diverse biological activity. A new method for synthesis of 2-(substituted phenyl)benzo[d]thiazole (3a-i) are developed by using simple method and good yields. We have synthesized more than thirty molecules in gram scale. This method is extremely useful for the synthesis of Benzothiazole derivatives in excellent yields.

Synthesis of some benzothiazole derivatives by using zinc oxide nanoparticles.