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ABSTRAKPenelitian bertujuan untuk mengkaji pengaruh penambahan ramuan herbal yang dikombinasikan dengan ekstrak kerang bakau (Polymesoda erosa) di dalam pakan terhadap kadar kolesterol, asam urat dan glukosa darah ayam buras. Penelitian menggunakan 100 ekor ayam buras yang dipelihara mulai dari umur satu hari (DOC) sampai dengan umur 16 minggu. Penelitian menggunakan rancangan acak lengkap dengan 5 perlakuan dan 4 ulangan. Perlakuan terdiri atas R0 (pakan basal + 0% probiotik herbal + 0% ekstrak kerang bakau), R1 (pakan basal + 0,75% probiotik herbal + 1,5% ekstrak kerang bakau), R2 (pakan basal + 1,5% probiotik herbal + 3% ekstrak kerang bakau), R3 (pakan basal + 2,25% probiotik herbal + 4,5% ekstrak kerang bakau) dan R4 (pakan basal + 3% probiotik herbal + 6% ekstrak kerang bakau). Data yang diperoleh dari hasil penelitian dianalisis menggunakan sidik ragam dan dilanjutkan dengan uji jarak berganda Duncan. Hasil penelitian menunjukkan bahwa rataan kolesterol darah yang diperoleh adalah berturut-turut 185,00±7,30 (P0), 185,75±6,80 (P1), 153,25±19,06 (P2), 167,75±17,72 (P3), 214,00±19,18 (P4). Rataan asam urat dalam darah yang diperoleh adalah 3,95±0,58 (P0), 6,70±4,23 (P1), 4,10±0,64 (P2), 4,32±1,27 (P3), 6,30±2,27 (P4). Sedangkan rataan glukosa darah yang diperoleh adalah 231±20,19 (P0), 188,50±24,63 (P1), 223,50±32,19 (P2), 227,25±68,61 (P3), 236,50±28,43 (P4).   Berdasarkan hasil penelitian dapat disimpulkan bahwa pemberian ramuan herbal dan ekstrak kerang bakau dalam pakan dapat mempengaruhi kadar kolestrol darah, namun tidak mempengaruhi kadar asam urat dan glukosa darah ayam buras. Kadar kolesterol darah terendah diperoleh pada perlakuan R2 dan R3 yang nyata berbeda dengan perlakuan R0, R1 dan R4.Kata Kunci: ayam buras, ramuan herbal, kolesterol, asam urat, glukosa darah.ABSTRACTKeywords:  blood glucose, cholesterol, herbal concoction, uric acid, village chickenThe objectives of this research was to evaluate the effect of agricultural by product-based feed supplemented with herbal concoction (HC) and mud clams extract (MC) on blood cholesterol, uric acid and blood glucose concentration. Completely randomized design was used with 4 treatments and 4 replications.  Ninety day old chick of local village chicken was used in this experiment and kept up to 16 weeks during the experiment. The treatments consisted of basal feed (R0), basal feed + 0.75% HC + 1.5% MC (R1), basal feed + 1.5% HC + 3.0% MC (R2), basal feed + 2.25% HC + 4.5% MC (R3), basal feed + 3.0% HC + 6.0% MC (R4).  All data were analyzed using analysis of variance and different between treatments were proved using Duncan multiple range test. The results showed that the concentrations of blood cholesterol gained (mg/dl) were 185.00±7.30 (P0), 185.75±6.80 (P1), 153.25±19.06 (P2), 167.75±17.72 (P3), 214.00±19.18 (P4). The concentration of uric acid gained (mg/dl) were 3.95±0.58 (P0), 6.70±4.23 (P1), 4.10±0.64 (P2), 4.32±1.27 (P3), 6.30±2.27 (P4). Whereas, the glucose concentration gained (mg/dl) were 231.00±20.19 (P0), 188.50±24.63 (P1), 223.50±32.19 (P2), 227.25±68.61 (P3), 236.50±28.43 (P4). Based on variance analysis it was concluded that the treatments gave a significant effect (P 0.05) on uric acid and blood glucose concentration. Blood cholesterol concentrations were significant lower in treatment R2 and R3 compared to treatment R0, R1 and R4.Keywords:  blood glucose, cholesterol, herbal concoction, uric acid, village chicken

Kolesterol, Asam Urat, dan Glukosa Darah Ayam Buras yang Diberi Pakan dengan Ramuan Herbal dan Ekstrak Kerang Bakau (Polymesoda erosa)