Open AccessNON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS), FREE RADICALS AND REACTIVE OXYGEN SPECIES (ROS): A REVIEW OF LITERATURE
Author(s) -
K Mahmood,
Jawad Ahmed,
Abdullah M. Jawad
Publication year - 2009
Publication title -
the medical journal of basrah university
Language(s) - English
Resource type - Journals
eISSN - 2413-4414
pISSN - 0253-0759
DOI - 10.33762/mjbu.2009.49041
Subject(s) - reactive oxygen species , oxidative stress , antioxidant , radical , pharmacology , chemistry , oxidative phosphorylation , anti oxidant , biochemistry , medicine
A wide controversy exists regarding the effect of NSAIDs on the oxidative status. Each member of these NSAIDs has been shown to act both as antioxidant or pro-oxidant in different test systems, using different concentrations and various oxidative stress-inducing agents. This review tackles this problem and tries to look for factors that might be responsible for this variation in results.
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