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This short communication reports the comparison of the reaction between morpholine with 4-bromobenzaldehyde in the condition with and without copper (I) iodide (CuI) as the catalyst. The reactions werecarried out at 110 oC under reflux condition for 24 hours, and the products were analysed using gaschromatography mass spectroscopy (GCMS). The GC results showed that the conversion of the product withoutCuI catalyst was higher than the reaction with catalyst under the same condition. Side product also was observedin the reaction without catalyst, which is because the morpholine was actually also attacked to the carbon in thecarbonyl group of 4-bromobenzaldehyde to produce 4-bromobenzoic acid morpholide.

The Study of the Reaction of Morpholine with 4-Bromobenzaldehyde in the Presence and Absence of Copper(I) Iodide