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The local and peritoneal recurrence play a vital role in the natural history of the evolution of gastrointestinal and ovarian neoplasms. Different methods of applying intraperitoneal chemotherapy were used perioperatively to consolidate or control peritoneal carcinomatosis [1]. The use of chemotherapy directly in the peritoneal cavity allows the direct action of the therapeutic agent in the metastatic nodules, increasing the local concentration with a limited increase in the systemic concentration. [1] The use of chemotherapy directly in the peritoneal cavity allows the direct action of the therapeutic agent on the metastatic nodules, increasing local concentration with a limited increase in systemic concentration [2-4]. The use of hyperthermia (HIPEC), early application in the postoperative period (EPIC) and Hipec laparoscopic L-HIPEC are different methods of application that seek to explore advantages with hyperthermia, application timing and multiple applications as advantages in the control of peritoneal disease. With this same objective, Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) has led to a more efficient process of delivering intraperitoneal chemotherapy.

Aerosol Distribution Pattern of a Single-port Device: New Perspective Treatment for Peritoneal Carcinomatosis in Brazil