English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Phosphonylation of kojic acid has been achieved using inorganic diphosphonate (DP) in aqueous solution. The optimum condition for the phosphonylation of kojic acid with DP is kojic acid : DP = 0.1 mol/L : 0.5 mol/L, pH 9 and 25 oC. 2-Phosphonylmethyl-kojic acid was synthesized with the yield of 45 %. The reaction mechanism of kojic acid with DP was discussed. We have successfully introduced the phosphonate group in kojic acid. Phosphonylated kojic acid is expected that the permeability of kojic acid into the skin will be increased by introducing a phosphonate group. (Received Nov 2, 2019; Accepted Nov 18, 2019)

INTRODUCTION OF PHOSPHONATE GROUP INTO KOJIC ACID BY DIPHOSPHONATE