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There exists a unique class of orthophosphates in which both the phosphorous and metal atoms are tetrahedrally coordinated by oxygen, therefore, to form metal phosphates. Various kinds of metal phosphate particles have many applications of uses in pigments, catalysis, adsorbents, and bioceramics. It is well known that calcium hydroxy apatite(Hap), a kind of calcium phosphate particles, also shows a high affinity for proteins and much attention has been focused on Hap and substituted Hap nanocrystals as sorbents. In this review, I will present (1) the preparation and characterization of monodispersed metal phosphate particles and (2) characteristics of protein adsorption onto various kinds of apatite particles based on our previous investigations.

PREPARATION AND CHARACTERIZATION OF MONOSDISPERSED METAL PHOSPHATE PARTICLES AND CHARACTERISTICS OF PROTEIN ADSORPTION ONTO VARIOUS APATITE PARTICLES