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Stem cells or progenitor cells have been demonstrated as a novel alternative for cell therapy; however, their sustained efficacy is still debated. This study aimed to evaluate whether interleukin 10 (IL-10) gene-edited amniotic mesenchymal stem cells (AMM/I) contribute to left ventricular (LV) function and remodeling after acute myocardial infarction (AMI).

Interleukin 10–Secreting MSCs via TALENMediated Gene Editing Attenuates Left Ventricular Remodeling after Myocardial Infarction