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The investigation on the toxigenic fungi growing in “home-made” miso was carried out. 173 samples from the farmhouse in Tohoku area were collected and surveyed but not so much contaminated with fungi. Citreoviridin from P. citreo-viride, viridicatin and viridicatol from P. cyclopium, rugulosin from P. rugulosum, and a new tremorgenic toxin, fumitremorgin from A. fumigatus were detected respectively as the important mycotoxins. A strain of Stachybotrys which was strongly toxic to mice was also isolated. However, from the EtOAc extracts of 25 strains of A. flavus-oryzae and 5 strains of A. ochraceus, neither aflatoxins nor ochratoxins were detected by TLC analysis.

On the Toxic Metabolites of the Fungi Isolated from “Home-Made” Miso