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Background: Chronic kidney disease (CKD) is a global health problem, with very high cost of care and greater burden particularly in developing countries like India. Material and Method: This prospective observational study of effects on hemoglobin and red cell indices in CKD before and after hemodialysis conducted on 150 CKD patients in SRM Medical College Hospital & Research Centre. Results: The most frequent morphologic features were normochromic-normocytic (78.7%), microcytic hypochromic (14.7%), macrocytic (3.3%) and dimorphic (3.3.%). Haemoglobin (Hb) levels and platelets counts are significantly reduced in post dialysis with a mean level of Hb 8.7 when compared to pre dialysis mean value of 7.78g/dL. There was a significant increase in MCV, with decrease in MCH and MCHC in the post dialysis values compared to pre dialysis. Conclusion: These hematological abnormalities expose CKD patients to higher risk of anemia-related complications. The present investigation might help clinicians to initiate precautions before and after dialysis procedures.

Effects of haemodialysis on Hemoglobin and red cell indices in chronic kidney disease patients at a tertiary health care institute