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The ease with which endotracheal intubation is performed depends upon degree of muscle relaxation, depth of anaesthesia and skill of anaesthesiologist. This is prospective, randomised observational study conducted at Deccan academy of Medical Sciences and Research Centre, Hyderabad. The aim of this study is to compare the effect of suxamethonium, vecuronium and rocuronium on intubation time and intubating conditions when used along with rocuronium. 75 patients aged between 30 to 50 year of both genders, weighing from 40 to 70kg coming for elective surgeries under general anaesthesia included. They are divided in three groups, Group 1received 0.6 mg/kg rocuronium, and Group II received Suxamethonium1.5 mg/kg. And group III vecuronium 0.1 mg/kg. Intubating conditions were assessed by cooper scoring system. In Group I, 15patients showed excellent, 10 patients good and no patients showed poor intubation conditions and in group II all patients (25) showed excellent, and group III all patients showed good intubation conditions respectively. The onset time of intubating condition of three groups were 82.95±20.34 in Group I compared with 60.25±9.41 in Group II whereas in group III 154.5±6.47. These timings were significantly reduced in Group II compared to Group I and Group III. Vecuronium 0.1 mg/kg produces good intubation conditions at 60 sec when compared with Vecuronium 0.8 mg/kg provides excellent intubating conditions within 60–66 secs without any adverse effects in elective surgeries in patients with stable haemodynamics.

A comparative study on different doses of suxamethonium, rocuronium and vecuronium with respect to onset time action and side effects