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An unusually high incidence of disseminated Frierman (1976) reported epizootic neoplasia (31 of neoplasia was found in a single year class of juvenile oysters 369 individuals; 8.4 in 2 inbred strains of juvenile surveyed histologlcally in lower Deldware Bay, New Jersey, eastern oysters from Chesapeake Bay, Virginia, USA, USA. Neoplasms were found on 13 of the 18 collection dates, and in 19 of the 834 oysters sampled, between 23 April and 24 He contrasted this with a much lower prevalence October 1991. No cases were found among the more than among other inbred and wild oysters from the 2200 other juvemle oysters examined fro111 1988 to 1994. The same area that were examined histo1ogica11.y between prevalence pattern of neoplasia followed that of gameto1964 and 1976 (39 of 51 000 Individuals; 0,076~yo), ~h~ genesis, suggesting some link with the reproductive process. although oysters with neoplasia generally had lower gonadal Haskin Shellfish Research Laboratory has a similarly indices than those without the disorder. The occurrence of long of examining eastern oysters diseases neoplasia in this group of oysters was associated with excep(1958 to 1995) and finding only very occasional neotionally heavy setting of that year class. The resulting extreme crowding may have stressed the oysters and would have fostered transmiss~on of a putative infect~ous agent.

Disseminated neoplasia in juvenile eastern oysters Crassostrea virginica, and its relationship to the reproductive cycle