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Coregonid larvae were found to suffer high mortality during the first days of feeding when reared on live zooplankton from their natural habitat. Histological studies on 7, 13, and 20 d old larvae suggested that these losses were caused by pathological alterations in the larvae's intestine. The symptoms observed include epithelial hyperplasia, dysplasia, and complete intestinal epithelial necrosis. These changes are compared with the normal histological differentiation found in larvae reared on Artemia nauplii. It is concluded that some component of lake plankton acts as a stressor to the larvae's intestinal epithelium and provokes the histopathological alterations which finally lead to the larvae's death.

Histopathological alterations in the intestine of whitefish {Coregonus sp.) larvae reared on zooplankton from Lake Constance