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Irritation fibromas are very common hyperplastic lesions of the oral mucosa, although there have been few studies of large numbers of cases. Clinicopathological features of this type of lesion were examined in 129 lesions in 124 patients, consisting of 47 males and 77 females. The peak incidence of the lesion was in the 6th decade of life. The lesions occurred in the tongue (n=66), the buccal mucosa (n=42), the labial mucosa (n=14), and the hard palate (n=7). All of the lesions were excised totally, and no recurrence was reported in any of the cases. Histologically, the lesions were divided into “radiating” type (n=105) and “circular” type (n=24) according to Barker & Lucas (1967). The incidence of the lesions in the buccal and labial mucosae was higher in the circular type of lesions (83.3%) than in the radiating type of lesions (34.3%), with a significant statistical difference (p<0.05). This supports the hypothesis that a low level of trauma or mechanical irritation might produce a radiating lesion on fixed mucosa and a circular lesion on mobile mucosa.

Irritation Fibroma of the Oral Mucosa: A clinicopathological study of 129 lesions in 124 cases.