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TGF-β1, TGF-βRI and TGF-βRII were examined in 80 cases of squamous cell carcinoma (SCC), 26 cases of leukoplakia and 10 cases of early carcinoma in leukoplakia of the tongue by immunohistochemical methods. Nine cases of SCC were analyzed immunoelectron microscopically. Expression of TGF-β1 was enhanced in SCC compared with early carcinoma in leukoplakia and with leukoplakia (P

oral medicine and pathology

Expression of Transforming Growth Factor (TGF)-.BETA.1 and its Type I and Type II Receptors in Carcinoma and Leukoplakia of the Tongue: Immunohistochemical and immunoelectron microscopic studies.