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Extended spectrum beta-lactamases (ESBLs) are cephalosporinases that confer resistance to a wide variety of oxyimino cephalosporins and create serious therapeutic problems. In addition, the quinolone resistance qnr genes are becoming increasingly prevalent in clinical isolates, some of which also produce ESBL. This study was designed to evaluate the occurrence and genotypic distribution of ESBL producing Escherichia coli (E. coli) and Klebsiella pneumoniae (K. pneumoniae) as well as the prevalence and distribution of qnr genes in ESBL-producing isolates in a tertiary care hospital in Korea.

yonsei medical journal/yonsei medical journal

Molecular Characteristics of Extended Spectrum β-Lactamases inEscherichia coliandKlebsiella pneumoniaeand the Prevalence ofqnrin Extended Spectrum β-Lactamase Isolates in a Tertiary Care Hospital in Korea