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Methionine synthase (MTR) and 5,10-methylenetetrahydrofolate reductase (MTHFR) are the main regulatory enzymes for homocysteine metabolism. The present case- control study was conducted to determine whether there is an association between the MTR 2756A &gt; G or MTHFR 677C &gt; T polymorphism and plasma homocysteine concentration in Korean subjects with ischemic stroke.

yonsei medical journal/yonsei medical journal

Influence of Combined Methionine Synthase (MTR 2756A &gt; G) and Methylenetetrahydrofolate Reductase (MTHFR 677C &gt; T) Polymorphisms to Plasma Homocysteine Levels in Korean Patients with Ischemic Stroke