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Contrast-induced localized orbitofacial edema is one of the moderate contrast-induced adverse reactions. Adverse reaction occurs in less than 1% of patients, as low as 0.35%, according to a recent study based on domestic data. The systems range from mild to severe cardiopulmonary collapse (1). Mostly, there are mild symptoms such as skin rashes, flushing, or mild urticaria (2). These mild symptoms generally do not require treatment with self-limiting features (2), but proper management must be done should the symptoms worsen (2). The researchers experienced a rare case of contrast-induced localized orbitofacial edema appearring on enhanced computed tomography (CT). The orbitofacial swelling on an enhanced CT image was the result of a contrast-induced adverse reaction, because the findings had not manifested before intravenous administration of contrast agent, and it was naturally resolved without treatment.

Transient Orbitofacial Angioedema due to Intravenous Iodinated Contrast Media During Computed Tomography: CT Findings