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Glufosinate ammonium (GLA) is a broad-spectrum herbicide used worldwide. As the use of GLA-containing herbicides has increased, poisoning from incidental and deliberate ingestion has also increased, and has been mostly reported from Japan. Most of glufosinate poisoning events were associated with suicide attempts using BASTA® (Bayer, Leverkusen, Germany). BASTA®, a herbicide containing glufosinate ammonium (18.5%) and the anionic surfactant, polyoxyethylene alkylether sulfate (30%), has been widely used in many countries since 1984 (1). Glufosinate poisoning has been reported to induce central nervous system (CNS) symptoms, such as drowsiness, memory impairment, and seizures. Also, the included anionic surfactant, which increases blood vessel permeability, may cause symptoms such as reduced circulatory blood volume, altered cardiac function, and systemic peripheral vessel resistance (1). Periventricular white matter ischemias, hippocampal lesions, and both hippocampal and striatal lesions have been reported following GLA intoxication, together with radiological findings (2, 3). We describe a patient who developed a reversible callosal lesion by ingesting a GLA-containing herbicide in an attempted suicide.

Reversible Splenial Lesion in the Corpus Callosum on MRI after Ingestion of a Herbicide Containing Glufosinate Ammonium: A Case Report