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. During pregnancy, several changes occur in the hematological parameters. The computerized blood count is one of the most useful tools to analyze them, being recommended by the World Health Organization for anemia diagnosis. However, not all the parameters obtained are employed in the clinical practice for the diagnosis of different pathologies or alterations during pregnancy. Objectives. To determine if the mean corpuscular volume (MCV) is related with the white blood cell (GB) count in pregnant women who attend to their regular controls at the National Maternal Perinatal Institute. Materials and methods. Observational cross-sectional study, composed of 8590 pregnant women attended in the National Maternal Perinatal Institute in Lima. An automated analysis was performed with the Mindray BC5800 25-parameter equipment. Statistical software STATA version 15.0 was used. The data are presented as means ± standard error, the variable VCM was categorized as normal (80≤MCV≤97fL), low (MCV <80fL) and high (MCV> 97fL). The ANOVA test was performed to determine the statistical difference between the MCV categorization groups and the various hematological parameters, followed by the post-hoc Scheffé test if significant. Linear regression was performed to determine the coefficient of the MCV categorization groups and their variation with the White Blood Cell count. Results. High MCV in pregnant women is associated with an increase of GB. In the analysis of the various types of GB, all of them are increased except for neutrophils, when MCV is high. Platelets show a lower value in the high MCV category as opposed to the normal and low VCM categories. Conclusions. High MCV could be associated with inflammation, as evidenced in the high number of the different GB except for neutrophils.

El volumen corpuscular medio alto se asocia con un aumento de los glóbulos blancos en el embarazo