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Purpose: A giant macular hole with retinal detachment occurred in a patient who had undergone several surgical treatments for retinal detachment, macular hole, and complicated cataracts. Here we report a case of successful retinal attachment and macular hole closure for this patient after autologous retinal flap transplantation. Case summary: Recently, an 18-year-old female presented with a newly developed visual field disturbance in her left eye. She had been on medication for severe atopic dermatitis in the past and seven years ago underwent scleral buckling, pars plana vitrectomy, and complicated cataract surgery due to rhegmatogenous retinal detachment of the left eye. Five years ago, extensive internal limiting membrane peeling, intravitreal gas tamponade, and aftercataract removal were performed due to the development of a macular hole with retinal detachment of the left eye. Thereafter, although the retina was reattached, closure of the macular hole was not successful. Recently, a giant macular hole with a retinal detachment was detected in this patient accompanied by symptoms of visual disturbance. Autologous retinal flap transplantation and intravitreal silicone oil tamponade were performed. Two months after the operation, she underwent silicone oil removal. Successful closure of the macular hole and retinal reattachment were confirmed. Conclusions: In a patient with a refractory giant macular hole with retinal detachment, the closure of the hole and retinal reattachment were successfully achieved after retinal flap transplantation, without viscoelastics or perfluorocarbon liquid. J Korean Ophthalmol Soc 2020;61(9):1090-1094

Autologous Retinal Flap Transplantation of a Refractory Giant Macular Hole with Retinal Detachment