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Purpose: To evaluate the clinical and radiological differences between the strabismus surgery and non-surgery groups in patients with Graves' ophthalmopathy. Methods: From January 2009 to January 2019, 20 patients who underwent strabismus surgery and 225 patients who did not undergo strabismus surgery were retrospectively analyzed using medical records. The mean age of the patients, the presence of smoking, the presence of hypertension and diabetes mellitus, anti-thyroid peroxidase antibody levels, anti-thyroglobulin antibody levels, thyroid stimulating hormone (TSH) receptor antibody levels, the presence of steroid therapy, the presence of radiation therapy, soft tissue scores, clinical activity scores (CASs), using methimazole, the presence of exophthalmos, and the maximal cross-sectional areas of the inferior and medial rectus muscles using computed tomography (CT) were compared between the two groups. Results: There was no statistically significant difference in sex, smoking, the presence of hypertension and diabetic mellitus, anti-thyroid peroxidase antibody levels, anti-thyroglobulin antibody levels, steroid therapy, radiation therapy, soft tissue scores, CASs, using methimazole, and the presence of exophthalmos between the strabimus surgery and non-surgery groups (p = 0.472, p = 0.523, p = 0.537, p = 0.751, p = 0.107, p = 0.195, p = 0.320, p = 0.071, p = 0.562, p = 0.144, p = 0.663, and p = 0.423, respectively). The mean age of the patients, TSH receptor antibody levels, and the averages of the maximal cross-sectional areas in the medial and inferior rectus muscles were significantly different between the two groups (p = 0.034, p = 0.042, p = 0.001, and p = 0.038, respectively). Conclusions: In patients with Graves’ ophthalmopathy, the risk factors for ocular motility disorders requiring strabismus surgery were not significant except for age, TSH receptor antibody levels, and the average of the maximal cross-sectional areas in inferior and medial rectus muscles using a CT scan. J Korean Ophthalmol Soc 2020;61(5):459-465

Comparision of Patient Characteristics in Graves’ Ophthalmopathy with and without Strabismus Surgery