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Adaptation of migrants to the conditions of the Russian North is largely determined by the state of the cardiovascular system. Registration of its changes due to environmental influences is associated with significant difficulties due to loss of sample homogeneity and the emergence of the Eskov-Zinchenko effect. Objective: to study the problem of loss of homogeneity in samples of RR (cardiointervals) in different age groups. Methods: samples of RR intervals of were recorded using the Eloks-01 device in three age groups of migrant women of Khanty-Mansi Autonomous Okrug (KhMAO) - Yugra. For recorded samples, matrices of paired comparisons of samples of cardiointervals and phase portraits (in 2 coordinates) were calculated. Results: calculated matrices of comparisons in pairs of samples of RR parameters steadily demonstrate a certain increase in the number of pairs (k), which have one (for this pair) common general population. The areas S of quasi-attractors, on the contrary, for cardiointervals (RR), decrease slightly with age, which can be described as a quadratic regression equation. Conclusions: All three age groups of women (alien population of KhMAO) demonstrate a steady loss of homogeneity of groups with changes in samples of cardiointervals, which confirms the validity of Eskov-Zinchenko effect. Moreover, such instability is more pronounced for individual test person than for age groups. It is proposed to calculate the parameters of quasi-attractors to assess differences in homeostasis of cardiovascular system, depending on the age of subjects. The areas S of quasi-attractors decrease with age (when normal aging), but for older-age migrants we have some increase in this area (possibly due to increase in pathological deviations in the cardiovascular system) which is not typical for indigenous population.

THE PROBLEM OF HOMOGENOUS SAMPLING OF CARDIOVASCULAR SYSTEM PARAMETERS AMONG MIGRANTS IN THE RUSSIAN NORTH