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. An innovative antifungal agent based on hydrochloride with combination of PEG-400 and PEG-1000 has been developed based at the chairs of Sechenov University. This solution is designated for external application as an antifungal agent. Naftifine hydrochloride has a broad spectrum of action against various fungi capable of causing onychomycosis. PEGs, forming part of the developed dosage form, bring about necessary viscosity of the solution (for retention in application area) and do not prevent drug product performance. Naftifine hydrochloride has an apparent UV absorption band with maximum of 256 ± 2 mn, in connection with this, it is supposed to use the UV spectrophotometry method for further development of quantitation method of naftifine hydrochloride detection in tested oral liquid. Методы анализа лекарственных средств Analytical Methods © Косенкова С. И., Краснюк И. И., Краснюк И. И. (мл.), Беляцкая А. В., Степанова О. И., Нарышкин С. Р., 2020 © Kosenkova S. I., Krasnyuk I. I., Krasnyuk I. I. (jr.), Belyatskaya A. V., Stepanova O. I., Naryshkin S. R., 2020

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Evaluation of the Possibility of Using the Method of UV Spectrophotometry for the Development of Quantitative Determination of Naftifine Hydrochloride in its Solution with a Combination of PEG for the Treatment of Fungal Infections