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Foot and mouth disease (FMD) is a severe, highly contagious, and economically devastating viral disease which affects domestic cloven-hoofed cattle, pigs, sheep, goats as well as more than 70 species of mammals (Barnett & Cox, 1999; Brown, 2003; Grubman & Baxt, 2004; Du et al., 2007; Giasuddin et al., 2016). FMD is prevalent in many parts of the world and notorious for its ability to severely affect and indeed disrupt regional and international trade in animals and animal products. FMD is very common in many parts of the world, particularly in developing countries of Asia, Africa, the Middle East, and some parts of Europe. The occurrence of FMD in these countries results in severe economic losses. In FMD-endemic countries, usually the developing countries, the disease threatens food security and the livelihoods of smallholders. This disease causes an economic loss of US$60–150 million annually in Bangladesh (Momtaz et al., 2014).

Occurrence of Foot and Mouth Disease (FMD) during 2014-2016 in cattle of Sirajganj district, Bangladesh