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A study of antimicrobial sensitivity of Escherichia coli ( E. coli ) isolated from clinical sources of different diagnostic centers of Dhaka, Bangladesh was carried out to facilitate the choice of drug in the management of E. coli induced symptoms. Very low sensitivity of E. coli towards ampicillin (4%), aztreonam (4%), cloxacillin (5%), nalidixic acid (5%), ciprofloxacin (7.5%), ceftriaxone (12.5%), doxycycline (12.5%), ceftazidime (16.25%), co-trimoxazole (20%), chloramphenicol (22.51%), tetracycline (25%), and netilmicin (35%) was observed. Higher sensitivity pattern was observed for gentamicin (56%) and only imipenem (95%) showed sensitivity pattern possibly susceptible enough to consider for the management of E. coli induced cases in the area under study. The low sensitivity to different antimicrobial could be attributed to their prevailing usage and abuse in the area under study. Key words: E. coli ; Antimicrobial sensitivity; Clinical isolates DOI: 10.3329/jbas.v34i1.5497 Journal of Bangladesh Academy of Sciences , Vol.34, No.1, 99-101, 2010

<i>In Vitro</i> Antimicrobial Sensitivity of <i>Escherichia coli</i> Isolated from Clinical Sources