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β -tocopherol ( 1 ), δ -tocopherol ( 2 ), polyprenol-12 ( 3 ), polyprenol-15 ( 4 ), stigmasterol and β -sitosterol were isolated from the yellow flavicarpa variety of leaves of Passiflora edulis . The structures of the isolated compounds were elucidated using 1 H-NR and 13 C-NMR spectral analysis. The organic and aqueous soluble fractions of crude methanolic extract were evaluated for the antioxidant, cytotoxic, thrombolytic and antimicrobial activities. In DPPH free radical scavenging assay, the aqueous soluble fraction displayed maximum activity having IC 50 value of 139.56μg/ml. On the other hand, dichloromethane soluble fraction revealed maximum cytotoxic (LC 50 24.17μg/ml) and thrombolytic (14.49% clot lysis) activities, when compared to the respective blanks. Dhaka Univ. J. Pharm. Sci. 16(1): 55-60, 2017 (June)

Tocopherols, Polyprenols and Steroids from Passiflora edulis and Bioactivities of its Extractives