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Nontuberculous mycobacteria (NTM) are a diverse group of ubiquitous environmental organisms and include more than 125 identified species broadly classifiable into “slow” and“rapid” growers. NTM are present in the environment, mainly in water, and are occasionally responsible for opportunistic infections in humans. Despite the fact that NTM are characterized by a moderate pathogenicity, the diseases caused by NTM at various body sites are increasing worldwide.1,2 Pulmonary involvement is the most common disease manifestation of NTM.3,4 Furthermore, patients with cystic fibrosis, the most frequent lethal genetic disorder of White persons, face numerous infectious pathogens over the course of their lifespan, increasing attention has recently been paid to NTM.5,6 Treatment of infections caused by NTM is either by drug therapy, surgery, or both. Drug therapy of NTM diseases is long, costly, and often associated with drug-related toxicities. The treatment regimens differ by species with the most important distinction being that between slow and rapid growing NTM.7

In vitro Evaluation of 2-/3-Alkoxyphenylcarbamic Acid Esters Containing N-Arylpiperazine Moiety Against Some Nontuberculous Mycobacteria