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Crude leaf extracts of Andrographis paniculata Burm. f. showed significant inhibition of growth and mutagenesis of N. crassa. Result showed that 1 ml extract can react with the test organism, Neurospora crassa very easily. During the period of 24 hours, it produced only 1.8 cm linear vegetative growth of the mycelia. Whereas 1 ml and 0.50 ml extracts produced less reactions (2.95 and 3.15 cm. respective- ly). The linear growth decreased with the increase of the concentrations of the extracts. Conidia of Ema (5297) of N. crassa were treated for 3-4 hours separately in 100% and 50% concentration of the extracts. One hundred percent extracts produced four types of mutants, namely- dirty, ropy, albino, and buff and 50% extracts produced three types of mutants, namely- plug, ropy (thin) and conidial brand.

bangladesh journal of scientific and industrial research

Growth Inhibition and Mutagenesis of &lt;i&gt;Neurospora crassa&lt;/i&gt; and the Same Organism by Leaf Extracts of &lt;i&gt;Andrographis paniculata&lt;/i&gt; Burm. f.