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01 * Correspondence: Professor Dr. S.M. Shamsuzzaman Department of Microbiology Dhaka Medical College, Dhaka Tel: 01819289739 Email: smszaman@yahoo.com Frequently we are facing bacteria which are resistant to most and in some cases all available antibiotics and we call them multidrug-resistant (MDR), extensively drug-resistant (XDR) and sometimes pandrug-resistant (PDR) bacteria 1,2,3 . Many different definitions of MDR, XDR and PDR bacteria are being used to characterize the different patterns of resistance 1,4. To overcome this problem. a joint initiative was taken by the European Centre for Disease Prevention and Control (ECDC) and the Centers for Disease Control and Prevention (CDC), to standardize definitions of MDR, XDR and PDR to describe acquired resistance profiles in bacteria responsible for healthcare-associated infections, such as., Staphylococcus aureus, Enterococcus spp., Enterobacteriaceae (other than Salmonella and Shigella), Pseudomonas aeruginosa and Acinetobacter spp5.

Multidrug-resistant, Extensively drug-resistant and Pandrug-resistant bacteria and antimicrobial therapy in combination.