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More than 112.5 million units of blood are collected from donors’ every year worldwide1. If safe blood transfusion is not performed, it can be life-threatening due to the transmission of blood-borne pathogens called transfusion transmissible infections (TTIs). TTIs include human immunodeficiency virus (HIV), hepatitis A, B, C, D, Treponema pallidum, malaria, West Nile virus (WNV), Cytomegalovirus (CMV), Human T-cell lymphotrophic viruses (HTLVs), Parvovirus B19, etc.2 According to CDC, TTIs may also result from new or emerging infectious agents e.g. new variant Creutzfeldt-Jacob Disease and recently emerging Chikungunya virus, with potential of transmission from person-to-person2-3. Globally, 170 million people are chronically infected with HCV, 350 million people with HBV and 38 million people are infected with HIV4. To assure the quality and safety, World Health Organization (WHO) recommends screening of at least major TTIs in donated blood5. It is estimated that 0.6 million units of blood are required annually in Bangladesh. All donated units of blood in the country must be screened for HIV, Hepatitis B and C, syphilis and malaria as per the Safe Blood Act 2002 and Safe Blood Transfusion Program (SBTP) 6. In 2010, the prevalence of TTI markers was found to be <1%6. However, the number of HIV and other TTIs is increasing in Bangladesh. To realize the true picture of TTIs in Bangladesh small rural districts should also be studied in addition to large city corporations e.g. Dhaka, Chittagong, etc. In the present study, prevalence of HIV, HBV, HCV and Treponema pallidum was investigated among volunteer blood donors in Shirajganj district, Bangladesh.

Prevalence of Transfusion Transmissible Infections (HBV, HCV, HIV and Treponema pallidum in Volunteer Blood Donors in Shirajganj District