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The daily recommended dose of vitamin A is 500 mcg in adult, 250-350 mcg in children and 600 mcg in pregnant woman2. Acute toxicity of vitamin A occurs within a few hours or days after ingestion of very large amount as a result of accidental overdose or inappropriate therapy. Children often got attracted to vitamin A capsule due to their attractive colours thus accidental ingestion may occur frequently. The estimated toxic dose is about 25,000 IU/kg. A single dose of >1 million units of vitamin A can also cause acute toxicity3. Chronic toxicity in older children and adults usually develop after doses of >50,000IU/day taken for months4. Both acute and chronic toxicity usually cause headache due to increased intracranial pressure. Here we wish to report this case of a 11 years old girl presented with diplopia and 6th nerve palsy, 24 hours after accidental ingestion of a large dose of vitamin A.

Diplopia and Acute Sixth Nerve Palsy in Hypervitaminosis A  A Case Report and a Review Literature

Diplopia and Acute Sixth Nerve Palsy in Hypervitaminosis A A Case Report and a Review Literature