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Mitral stenosisis a valvular heart disease caused by a number of diseases. Chronic rheumatic fever is the most important cause. Among rare causes, some rheumatoid diseases like SLE may involve cardiovascular system causing libman- sacks endocarditis,pericardial diseases and other valvular lesions mostly associated with positive antiphospholipid and anticardiolipin antibody.Here, we presented a case of rheumatic mitral valvular heart disease having systemic lupus erythromatosus but negative antiphospholipid and anticardiolipin antibody. Bangladesh Heart Journal 2016; 31(2) : 109-112

A Lady with Systemic Lupus Erythematosus and Mitral Stenosis