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Neurochemical transmitters in the brain lead speaking mechanism and its path by physical and chemical interactions in the various environments. Fundamental neurotransmitter ,Dopamine (DA), is infectious by Methamphetamine (Meth) through the language status; so this work strives to demonstrate the lack of language progress after blocking of DA by Meth while brain is not capable to manage the operation of learning. Meth is an important loss of DA transmitters which creates a reduced memory through the slower motor operation. Then, in this work, it has been discussed the damage of DA effectiveness in the brain by simulating the compounds of Meth, DA, MethDA , TiO2 nanosurface, and Meth-DA-TiO2 nanocluster due to discovering the effect of Methamphetamine (Meth) as a stopper of DA release in brain. Theoretical calculations have been run on these compounds to achieving the chemical and physical effects. So, it has been shown that after blocking of dopamine by Meth, brain cannot indicate its function for dispersing the neurochemical transmitters which cause the role of learning a foreign language.

Methamphetamine causes the exhilaration in the brain by dumping dopamine