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To the Editor: In a recent study published in the Croatian Medical Journal, Šegrt Ribičić et al (1) described the effect of dives using self-contained underwater breathing apparatus on endothelial function (flow-mediated dilatation). Endothelial function was reduced after diving to a depth of 45 m sea water for a bottom time of 20 min when breathing nitrox containing 50% oxygen, but not when breathing air or nitrox containing 99% oxygen. The authors claimed this was the opposite of what they would have expected, it being known that endothelial function is affected by hyperoxia.

croatian medical journal

Gas micronuclei underlying decompression bubbles may explain the influence of oxygen enriched gases during decompression on bubble formation and endothelial function in self-contained underwater breathing apparatus diving