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Hemophagocytic lymphohistiocytosis (HLH) is a rare but aggressive and potentially life-threatening syndrome caused by a hyperinflammatory response leading to organ damage.[1][1],[2][2] It is characterized by fevers, cytopenias, hepatosplenomegaly, hyperferritinemia, hypertriglyceridemia and

Recognition of hemophagocytic lymphohistiocytosis in sickle cell vaso-occlusive crises is a potentially lifesaving diagnosis