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Cancer-related anemia (CRA) is part of the broader group of anemias caused by inflammation, in which macrophages and inflammatory cytokines, in particular interleukin (IL)-6 and hepcidin, play a major role.[1][1],[2][2] Typically, CRA is characterized by low levels of serum iron, but high levels of

Microenvironmental M1 tumor-associated macrophage polarization influences cancer-related anemia in advanced ovarian cancer: key role of interleukin-6