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Mucosal associated invariant T (MAIT) cells primarily contribute to immune defense against infectious pathogens and regulate pathogenesis of various inflammatory diseases.[1][1] They are innate-like T lymphocytes expressing an invariant TCR Vα7.2-Jα33 chain in humans and displaying high expression

Both mucosal-associated invariant and natural killer T-cell deficiency in multiple myeloma can be countered by PD-1 inhibition