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Blood transfusion in β-thalassemia major aims to suppress ineffective erythropoiesis, limit morbidity from chronic anemia, and minimize bone changes from marrow expansion and extra-medullary hemopoiesis (EMH).[1][1] In the 1970s, blood transfusion was shown to suppress erythro-poiesis.[2][2] It is

Erythropoiesis is not equally suppressed in transfused males and females with thalassemia major: are there clinical implications?