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While the probability of troublesome adverse effects related to the transfusion of older red blood cell (RBC) units is still a matter of debate and of clinical investigation, what is now known for certain is that blood storage affects the biochemical and biological properties of RBCs. The

haematologica (roma)

Label-free quantitation of phosphopeptide changes in erythrocyte membranes: towards molecular mechanisms underlying deformability alterations in stored red blood cells