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Genetic aberrations affecting kinases have been widely studied in acute myeloid leukemia (AML). However, the role of phosphatases remains underexplored. Protein phosphatase 2A (PP2A) is a major serine/threonine phosphatase that participates in many signaling pathways.[1][1] Transformed cells present

Downregulation of PPP2R5E is a common event in acute myeloid leukemia that affects the oncogenic potential of leukemic cells