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Platelet morphological defects have previously been described in von Willebrand disease type 2B (VWD2B), we now describe that they may also occur in patients with VWD3 lacking both platelet and plasma von Willebrand factor (VWF). Electron microscopy (EM) and immunofluorescence labeling (IF) were

Platelet morphological changes in 2 patients with von Willebrand disease type 3 caused by large homozygous deletions of the von Willebrand factor gene