Open AccessMonitoring serum free light chains in patients with multiple myeloma who achieved negative immunofixation after allogeneic stem cell transplantation
Author(s) -
U. Mosbauer,
Francis Ayuk,
Heike Schieder,
Michael Lioznov,
A R Zander,
Nicolaus Kröger
Publication year - 2007
Publication title -
haematologica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.782
H-Index - 142
eISSN - 1592-8721
pISSN - 0390-6078
DOI - 10.3324/haematol.10568
Subject(s) - immunofixation , multiple myeloma , negativity effect , medicine , transplantation , immunoglobulin light chain , monoclonal , antibody , immunology , monoclonal antibody , psychology , social psychology
Monitoring of serum free immunoglobulin light chains (FLC) in 26 myeloma patients who achieved immunofixation negativity after allografting showed a decrease of FLC at a median of 128 days before immunofixation negativity. In patients who subsequently relapsed, a 25% increase of FLC was observed at a median of 98 days before immunofixation positivity.
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