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IFAP is an acronym for a rare congenital ectodermal disorder characterized by ichthyosis follicularis, alopecia and photophobia. A recessive X-linked mode of inheritance was initially proposed but recent reports in girls suggested genetic heterogeneity of this syndrome. We herein describe a 1-year-old boy with clinical features typical of IFAP syndrome plus psoriasis-like lesions and palmoplantar keratoderma (PPK).

journal of dermatological case reports

A new variant of ichthyosis follicularis with alopecia and photophobia (IFAP) syndrome with coexisting psoriasiform lesions and palmoplantar keratoderma. IFAP-PPK syndrome?