Superparamagnetic Iron Oxide Nanoparticles in Cancer Theranostics
Author(s) -
Mohammad Norouzi,
Soroosh Derakhshanfar,
Mohammad Reza Kazemian,
Rodrigo França
Publication year - 2018
Publication title -
advances in materials science and engineering
Language(s) - English
Resource type - Journals
ISSN - 2578-7217
DOI - 10.33140/amse/02/01/04
Subject(s) - materials science , nanotechnology , superparamagnetism , cancer therapy , magnetic resonance imaging , nanoparticle , biosafety , magnetic hyperthermia , cancer , magnetic nanoparticles , medicine , radiology , pathology , magnetic field , magnetization , quantum mechanics , physics
Superparamagnetic iron oxide nanoparticles (SPIONs) have found extensive applications in both cancer therapy and diagnosis (theranostics) due to their intrinsic magnetic properties. SPIONs can be applied as contrast agents in magnetic resonance imaging while they are considered as efficacious drug carriers for targeted therapeutic systems as well as hyperthermia therapy. In this article, recent advances in application of SPIONs in the realm of cancer theranostics are reviewed. Moreover, biosafety issues arising from SPION application are briefly mentioned.
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