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Aflatoxin produced by Aspergillus flavus is known to be strongly related to liver injury (hepatocellular carcinoma) and immune system damage involving leukocytes. This toxin suppresses both the cell-mediated immune system and macrophage function, and decreases the production of complement and interferon molecules.

Immunohistochemical Detection of Aflatoxin in Lesions of Aflatoxin-producing <i>Aspergillus flavus</i> Infection