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1Gastrointestinal Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK 2Department of Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK 3School of Medicine, University of Exeter, Exeter, UK 4Gastrointestinal Unit, Ninewells Hospital, Dundee, UK 5Gastrointestinal Unit, Western General Hospital, Edinburgh, UK 6Edinburgh Clinical Trials Unit, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK

efficacy and mechanism evaluation

A randomised, double-blind, parallel-group trial to assess mercaptopurine versus placebo to prevent or delay recurrence of Crohn’s disease following surgical resection (TOPPIC)